Research Archives - Critical Care Practitioner

Gavin raises his legs!!

Tweet The assessment of fluid responsiveness in haemodynamically unstable patients. My good friend Gavin Denton (@dentongavin) has once again surpassed himself in analysing some of the evidence for the passive leg raise. Over to you Gav (I think I love him….ssshhhh).   Background. Clinical examination and findings have long been used to guide fluid resuscitation. […]

The ALBIOS Trial: Albumin in Severe Sepsis?

Tweet The New England Journal of Medicine. 2014. 370(15):1402-141 Among patients with severe sepsis or septic shock, does administration of albumin 20% solution to maintain serum albumin level ≥3 g/dL reduce all-cause mortality at 28 days when compared to no albumin? Multi centre, open label. randomised trial. Inclusion criteria Suspected or proven infection in one […]

PROSEVA- proning in the ARDS patient.

Tweet Prone Positioning in Severe Acute Respiratory Distress Syndrome Claude Guérin, M.D., Ph.D., Jean Reignier, M.D., Ph.D., Jean-Christophe Richard, M.D., Ph.D., Pascal Beuret, M.D., Arnaud Gacouin, M.D., Thierry Boulain, M.D., Emmanuelle Mercier, M.D., Michel Badet, M.D., Alain Mercat, M.D., Ph.D., Olivier Baudin, M.D., Marc Clavel, M.D., Delphine Chatellier, M.D., Samir Jaber, M.D., Ph.D. NEJM 2013 This […]

CCP Podcast 023: Wash Your Mouth Out!!

Podcast: Play in new window | DownloadSubscribe: Apple Podcasts | RSSTweet Reducing ventilator associated pneumonia in adult patients through high standards of oral care: A historical control study Lee Cutler, Paula Sluman. Intensive and Critical care Nursing. 2014 Consultant Nurse Lee Cutler discusses the study he was involved in with his colleague Paula Sluman. Ventilator […]

Choice of Fluid- John Myburgh Summary.

Tweet Fluid resuscitation in acute medicine: what is the current situation?  Journal of internal medicine (Accepted Article) Professor John A Myburgh AO, is Director of the Division of Critical Care and Trauma at the George Institute for Global Health, Professor of Critical Care at the Faculty of Medicine, University of New South Wales and senior […]

ARISE Trial- Early Goal Directed Therapy Is Not The Gold Standard…

Tweet Goal-Directed Resuscitation for Patients with Early Septic Shock The ARISE Investigators and the ANZICS Clinical Trials Group   Emmanuel Rivers trial found a big difference in 90 day mortality when using early goal directed therapy and as a consequence the Surviving Sepsis Guidelines have advocated the use of this algorithm.  The recent PROCESS trial […]

Jones- Is Lactate a Useful Indicator?

Tweet Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: A Randomized Clinical Trial Dr. Alan E. Jones, MD, Dr. Nathan I. Shapiro, MD, MPH, Dr. Stephen Trzeciak, MD, MPH, Dr. Ryan C. Arnold, MD, Ms. Heather A. Claremont, BFA, and Dr. Jeffrey A. Kline, MD for the Emergency Medicine Shock […]

Mariks’ Deadly Trio!

Tweet Iatrogenic salt water drowning and the hazards of a high central venous pressure. Marik Annals of Intensive Care 2014, 4:21   Paul Marik has been investigating the effects of fluid on the septic patient over the years, publishing several important papers in the process. Does Central Venous Pressure Predict Fluid Responsiveness? CHEST 2008 Heamodynamic parameters […]

CCP Podcast 012: Get my feet to the floor…please!

Podcast: Play in new window | DownloadSubscribe: Apple Podcasts | RSSTweet ICU acquired weakness or polyneuropathy An interview with Dr John Kress, an ITU physician from the University of Chicago. Dr Kress is a highly respected and well published doctor with an interest in ICU acquired weakness or polyneuropathy, one of his more well known […]