Critical Care Practitioner
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    • Mechanical Ventilation: Why do we do it? Goals and Indications.
    • Mechanical Ventilation- Terminology
    • 6 Ways To Be Better With The Bag-Valve-Mask
    • Mechanical Ventilation Series- How lung compliance affects ventilation in volume controlled ventilation.
    • Mechanical Ventilation Series: Physiologic Goals of Mechanical Ventilation.
    • CCP Podcast 018: Mechanical Ventilation….
    • CCP Podcast 024: Mechanical Ventilation….the basics.
    • Mechanical Ventilation Series- A-a gradient.
    • Mechanical Ventilation Series- How do I describe how my patient is being ventilated?
    • Mechanical Ventilation: Physiologic effects of mechanical ventilation.
    • Mechanical Ventilation Series- Lung Compliance….
    • Mechanical Ventilation Series- Phase Variables…again…
    • Mechanical Ventilation Series- Pressure/Volume loop…..
    • Mechanical Ventilation- Anatomy of the Adult Endotracheal Tube
    • Mechanical Ventilation- Increase the Rate or the Tidal Volume?
    • Mechanical Ventilation- Modes of Ventilation I
    • Mechanical Ventilation- Modes of Ventilation II
    • Mechanical Ventilation- Peak Pressure and Plateau Pressure
    • Mechanical Ventilation- PEEP (Positive End Expiratory Pressure).
    • Mechanical Ventilation- Phase Variables.
    • Mechanical Ventilation- Phases of a breath- I:E ratio and total cycle time.
    • Mechanical Ventilation- Pressure/Volume/Flow loops
    • Mechanical Ventilation- Ventilation Screen, what do some of those numbers mean?
    • Mechanical Ventilation- Ventilation/Perfusion
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Sepsis- recognition and treatment

By Jonathan Downham On December 31, 2018 · Add Comment
Tweet Lecture given by Scott Weingart on sepsis and its recognition and treatment. Link Here
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Continuous beta-lactam infusion in critically ill patients: the clinical evidence

By Jonathan Downham On December 31, 2018 · Add Comment
Tweet Although numerous PK/PD data from various in vitro and in vivo experimental studies favor the use of continuous infusion, the current clinical data are less convincing and insufficient to instigate a global shift from conventional bolus dosing. However, this lack of convincing data may be due to several methodological flaws and inconsistencies among the [...]
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Fluids in sepsis

ProCESS- Get rid of the central line?

By Jonathan Downham On November 10, 2018 · 1 Comment
Tweet And the debate goes on! How much fluid should we give our septic patients? The results from the ProCESS trial are out and I am still not sure that we have an answer. So I listened to one of my go to guys to help me understand…..Scott Weingart. The Method Patients enrolled were those [...]
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Single-Dose Etomidate Is Not Associated With Increased Mortality in ICU Patients With Sepsis: Analysis of a Large Electronic ICU Database

By Jonathan Downham On September 7, 2018 · Add Comment
Tweet In a mixed-diagnosis group of critically ill patients with sepsis, severe sepsis, and septic shock, single-dose etomidate administration for intubation in the ICU was not associated with higher mortality or other adverse clinical outcomes….link here
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Continuous Infusion of Beta-Lactam Antibiotics in Severe Sepsis: A Multicenter Double-Blind, Randomized Controlled Trial

By Jonathan Downham On September 7, 2018 · Add Comment
Tweet Continuous administration of beta-lactam antibiotics achieved higher plasma antibiotic concentrations than intermittent administration with improvement in clinical cure. This study provides a strong rationale for further multicenter trials with sufficient power to identify differences in patient-centered endpoints….link here
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Association between Antibiotic Treatment and Outcomes in Patients Hospitalized with Acute Exacerbation of COPD Treated with Systemic Steroids.

By Jonathan Downham On August 30, 2018 · Add Comment
Tweet ABSTRACT BACKGROUND: Antibiotics are widely used in acute exacerbation of COPD (AE-COPD), but their additional benefit to a therapeutic regimen that already includes steroids is uncertain. We evaluated the association between antibiotic therapy and outcomes among a large cohort of steroid treated patients who were hospitalized with AE-COPD and compared the effectiveness of three [...]
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Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis*.

By Jonathan Downham On July 2, 2018 · Add Comment
Tweet Administration of etomidate for rapid sequence intubation is associated with higher rates of adrenal insufficiency and mortality in patients with sepsis…..link here
[Continue Reading...]
  • A Beginners Guide to Intubation

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  • Recent Posts

    • CCP Podcast 104: Post Intensive Care Syndrome in Critical Care February 26, 2019
    • CCP Podcast 103: Acute Right Heart Failure January 31, 2019
    • CCP Podcast 095: More mechanical ventilation with Thomas January 23, 2019
    • CCP Podcast 051: ICU Follow Up Clinics January 23, 2019
    • CCP Podcast 047: Advanced Critical Care Practitioners January 23, 2019
    • CCP Podcast 010: Cricoid Pressure: Do it? Do it right? Or don’t do it at all? January 23, 2019
    • CCP Podcast 029: Mechanical Ventilation…Phases of the Breath January 23, 2019
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