Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: a systematic review.

Tweet In mechanically ventilated patients without ARDS at the time of endotracheal intubation, the majority of data favors lower tidal volume to reduce progression to ARDS. However, due to significant heterogeneity in the data, no definitive recommendations can be made. Further randomized controlled trials examining the role of lower tidal volumes in patients without ARDS, […]

High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome

Tweet In conclusion, in adults with moderate-to-severe ARDS, the early application of HFOV targeting lung recruitment — as compared with a ventilation strategy that uses low tidal volume and high PEEP and that permits HFOV only in cases of refractory hypoxemia — does not reduce mortality and may be harmful…link here