- Fluid Resus
- Source Control
- Fluid Therapy
- Effects of perfusion pressure on tissue perfusion in septic shock.
- Increasing mean arterial pressure in patients with septic shock: effects on oxygen variables and renal function.
- Effects of changes in arterial pressure on organ perfusion during septic shock.
- High versus low blood-pressure target in patients with septic shock.
- Higher versus lower blood pressure targets for vasopressor therapy in shock
- Lactate and shock state: the metabolic view.
- Lactate measurements in sepsis-induced tissue hypoperfusion
- Early lactate-guided therapy in intensive care unit patients
- Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy
- Efficacies of fluid resuscitation as guided by lactate clearance rate and central venous oxygen saturation in patients with septic shock
- The effect of early goal lactate clearance rate on the outcome of septic shock patients with severe pneumonia
- Comparison of the effect of fluid resuscitation as guided either by lactate clearance rate or by central venous oxygen saturation in patients with sepsis
- Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
- Time to Appropriate Antibiotic Therapy Is an Independent Determinant of Postinfection ICU and Hospital Lengths of Stay in Patients With Sepsis.
- Influence of antibiotic therapy on mortality of critical surgical illness caused or complicated by infection
- Bundled care for septic shock: an analysis of clinical trials.
- Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department.
- Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic shock.
- Impact of compliance with infection management guidelines on outcome in patients with severe sepsis
- Surgical delay is a critical determinant of survival in perforated peptic ulcer.
- The impact of delayed biliary decompression and anti-microbial therapy in 260 patients with cholangitis-associated septic shock
- A positive fluid balance is an independent prognostic factor in patients with sepsis.
- Positive fluid balance as a major predictor of clinical outcome of patients with sepsis/septic shock after ICU discharge.
- Positive fluid balance as a prognostic factor for mortality and acute kidney injury in severe sepsis and septic shock.
- Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients
- The SAFE study: saline vs. albumin for fluid resuscitation in the critically ill.
The Bottom Line is an excellent resource for you to use. This is full of papers which have been reviewed by the team. They hep us understand the trial with its strengths and weaknesses and recommendations as to how seriously we should take to findings of each paper. The links below are to some important papers on this subject which they have reviewed.
Guidelines for the management of tracheal intubation in critically ill adults
Having read the guidelines I made these infographics. They are FREE. Just click on the button below.