CCP Podcast: Episode 1 A short history of sedation in ICU

In this episode, I explore how sedation practices in critical care have evolved over time — from the routine use of deep, continuous sedation to the early evidence that challenged it. You'll hear about pivotal studies that revealed the risks of over-sedation, the emergence of structured sedation protocols, and the beginnings of a culture shift toward lighter, more patient-centered care.

Key topics:

• The rise of continuous sedation in early ICU care

• Landmark studies questioning deep sedation

• Early implementation of sedation protocols

• How sedation culture began to change

 Kress et al. (1998). The use of continuous i.v. sedation is associated with prolongation of mechanical ventilation.

Brook et al. (2000). A prospective evaluation of empiric versus protocol-based sedation and analgesia.

Novaes et al. (1999). Stressors in ICU: perception of the patient, relatives, and health care team.

Martin et al. (2001). Sedative and analgesic practice in the intensive care unit: the results of a European survey